Cotreatment with Aspirin and Azole Drugs Increases Sensitivity of Candida albicans in vitro
نویسندگان
چکیده
منابع مشابه
Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
Within the limited antifungal armamentarium, the azole antifungals are the most frequent class used to treat Candida infections. Azole antifungals such as fluconazole are often preferred treatment for many Candida infections as they are inexpensive, exhibit limited toxicity, and are available for oral administration. There is, however, extensive documentation of intrinsic and developed resistan...
متن کاملAzole Drugs Are Imported By Facilitated Diffusion in Candida albicans and Other Pathogenic Fungi
Despite the wealth of knowledge regarding the mechanisms of action and the mechanisms of resistance to azole antifungals, very little is known about how the azoles are imported into pathogenic fungal cells. Here the in-vitro accumulation and import of Fluconazole (FLC) was examined in the pathogenic fungus, Candida albicans. In energized cells, FLC accumulation correlates inversely with express...
متن کاملMicafungin activity against Candida albicans with diverse azole resistance phenotypes.
OBJECTIVES The purpose of this study was to investigate whether mechanisms of azole resistance in Candida albicans contribute to reduced micafungin activity in vitro. METHODS MICs were determined for a collection of strains with well-characterized mechanisms of azole resistance obtained from systemic, oral and vaginal infections. This collection of strains includes those with resistance-assoc...
متن کاملeffects of aspirin as an anti-inflammatory drug on azole-resistant candida glabrata in vitro
no abstract
متن کاملin vitro susceptibility and trailing growth effect of clinical isolates of candida species to azole drugs
conclusions the monitoring of antifungal susceptibilities of candida species isolated from clinical sources is highly recommended for the efficient management of patients. moreover, the trailing effect should be taken into consideration once the interpretation of the results is intended. results among the tested antifungal drugs in this study, the highest rate of resistance was observed against...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Drug Resistance
سال: 2021
ISSN: 1178-6973
DOI: 10.2147/idr.s314538